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整合素樣金屬蛋白酶與凝血酶1型-7抗體
英文名稱:ADAMTS7(NT)總訪問(wèn):265
國(guó)產(chǎn)/進(jìn)口:國(guó)產(chǎn)半年訪問(wèn):9
產(chǎn)地/品牌:bioss產(chǎn)品類別:抗體
規(guī)       格:bs-0733R 最后更新:2017-5-3
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產(chǎn)品編號(hào) bs-0733R
英文名稱 ADAMTS7(NT)
中文名稱 整合素樣金屬蛋白酶與凝血酶1型-7抗體 (N端抗體)
別    名 A disintegrin and metalloproteinase with thrombospondin motifs 7; ADAM metallopeptidase with thrombospondin type 1 motif 7; A disintegrin and metalloprotease with thrombospondin motifs 7 preproprotein; A disintegrin and metalloproteinase with thrombospondin motifs 7; A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 7; A disintegrin like and metalloprotease with thrombospondin type 1 motif 7; ADAM metallopeptidase with thrombospondin type 1 motif 7; ADAM metallopeptidase with thrombospondin type 1 motif 7 preproprotein; ADAM TS 7; ADAM TS7; ADAMTS 7; ADA
規(guī)格價(jià)格 0.1ml/600元 購(gòu)買    0.2ml/1000元 購(gòu)買    
說(shuō) 明 書 0.1ml  0.2ml  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  激酶和磷酸酶  細(xì)胞骨架  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù)) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 158kDa
細(xì)胞定位 細(xì)胞膜 細(xì)胞外基質(zhì) 分泌型蛋白 
性    狀 Lyophilized or Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse ADAMTS7
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
生 產(chǎn) 商 BIOSS
PubMed PubMed
產(chǎn)品介紹 background:
Metalloprotease that may play a role in the degradation of COMP. Binds 1 zinc ion per subunit. pH dependence: Optimum pH is between 7.5 and 9.5. [Subcellular location] Secreted, extracellular space, extracellular matrix (By similarity). Note=Also found associated with the external cell surface[Tissue specificity] Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Detected in meniscus, bone, tendon, cartilage, synovium, fat and ligaments. Up-regulated in articular cartilage and synovium from arthritis patients.

Function:
Metalloprotease that may play a role in the degradation of COMP.

Subunit:
Interacts with COMP.

Subcellular Location:
Secreted, extracellular space, extracellular matrix. Note=Also found associated with the external cell surface.

Tissue Specificity:
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Detected in meniscus, bone, tendon, cartilage, synovium, fat and ligaments.

Post-translational modifications:
N-glycosylated. 
O-glycosylated proteoglycan. Contains chondroitin sulfate (By similarity). 
May be cleaved by a furin endopeptidase (By similarity). The precursor is sequentially processed. 

Similarity:
Contains 1 disintegrin domain.
Contains 1 peptidase M12B domain.
Contains 1 PLAC domain.
Contains 8 TSP type-1 domains.

Gene ID:
102248157

Database links:

Entrez Gene: 11173 Human

Omim: 605009 Human

SwissProt: Q6P7J9 Human

SwissProt: Q9UKP4 Human

Unigene: 16441 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

整合素樣金屬蛋白酶與凝血酶1型-7用于動(dòng)脈粥樣硬化導(dǎo)致早期血管基質(zhì)修復(fù)作用的研究
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